Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium

It has become evident that somatic mutations in cancer-associated genes accumulate in the normal endometrium, but spatiotemporal understanding of the evolution and expansion of mutant clones is limited. To elucidate the timing and mechanism of the clonal expansion of somatic mutations in cancer-asso...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Manako, Nakaoka, Hirofumi, Suda, Kazuaki, Yoshihara, Kosuke, Ishiguro, Tatsuya, Yachida, Nozomi, Saito, Kyota, Ueda, Haruka, Sugino, Kentaro, Mori, Yutaro, Yamawaki, Kaoru, Tamura, Ryo, Revathidevi, Sundaramoorthy, Motoyama, Teiichi, Tainaka, Kazuki, Verhaak, Roel G. W., Inoue, Ituro, Enomoto, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854701/
https://www.ncbi.nlm.nih.gov/pubmed/35177608
http://dx.doi.org/10.1038/s41467-022-28568-2

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