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Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention

Non-communicable diseases (NCDs) are the largest cause of disability and death globally. The human and financial costs of NCDs have raised questions of sustainability for many health systems. Personalized, preventive health interventions are an innovative way to address NCDs, but it is difficult to...

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Autores principales: Garton, Elise M., Savaş, Serdar, Pell, Christopher, Syurina, Elena V., Stronks, Karien, Cesuroglu, Tomris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854757/
https://www.ncbi.nlm.nih.gov/pubmed/35186838
http://dx.doi.org/10.3389/fpubh.2022.793137
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author Garton, Elise M.
Savaş, Serdar
Pell, Christopher
Syurina, Elena V.
Stronks, Karien
Cesuroglu, Tomris
author_facet Garton, Elise M.
Savaş, Serdar
Pell, Christopher
Syurina, Elena V.
Stronks, Karien
Cesuroglu, Tomris
author_sort Garton, Elise M.
collection PubMed
description Non-communicable diseases (NCDs) are the largest cause of disability and death globally. The human and financial costs of NCDs have raised questions of sustainability for many health systems. Personalized, preventive health interventions are an innovative way to address NCDs, but it is difficult to measure their effectiveness using standard evaluation methods. This article describes a novel approach to evaluation by coupling transdisciplinary methods with realist theory to design and pilot a health outcomes evaluation for a personalized medicine approach to NCD prevention in Istanbul, Turkey. Research and practice stakeholders contributed to study design, research questions, validation of results, and recommendations through interactive workshops, consistent dialogue, and reflection. They co-created a customized outcome measurement framework and recommendations that promote sustainability and continuous improvement of future evaluations. The participatory methods helped resolve the dichotomy between patient, practitioner, and researcher focus in the evaluation and improved stakeholders' data literacy. This research contributes to the body of evidence advocating for the use of non-standard methods such as transdisciplinary research to evaluate the effectiveness of complex interventions. The results of the pilot evaluation are also presented as a case study.
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spelling pubmed-88547572022-02-19 Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention Garton, Elise M. Savaş, Serdar Pell, Christopher Syurina, Elena V. Stronks, Karien Cesuroglu, Tomris Front Public Health Public Health Non-communicable diseases (NCDs) are the largest cause of disability and death globally. The human and financial costs of NCDs have raised questions of sustainability for many health systems. Personalized, preventive health interventions are an innovative way to address NCDs, but it is difficult to measure their effectiveness using standard evaluation methods. This article describes a novel approach to evaluation by coupling transdisciplinary methods with realist theory to design and pilot a health outcomes evaluation for a personalized medicine approach to NCD prevention in Istanbul, Turkey. Research and practice stakeholders contributed to study design, research questions, validation of results, and recommendations through interactive workshops, consistent dialogue, and reflection. They co-created a customized outcome measurement framework and recommendations that promote sustainability and continuous improvement of future evaluations. The participatory methods helped resolve the dichotomy between patient, practitioner, and researcher focus in the evaluation and improved stakeholders' data literacy. This research contributes to the body of evidence advocating for the use of non-standard methods such as transdisciplinary research to evaluate the effectiveness of complex interventions. The results of the pilot evaluation are also presented as a case study. Frontiers Media S.A. 2022-02-04 /pmc/articles/PMC8854757/ /pubmed/35186838 http://dx.doi.org/10.3389/fpubh.2022.793137 Text en Copyright © 2022 Garton, Savaş, Pell, Syurina, Stronks and Cesuroglu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Garton, Elise M.
Savaş, Serdar
Pell, Christopher
Syurina, Elena V.
Stronks, Karien
Cesuroglu, Tomris
Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention
title Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention
title_full Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention
title_fullStr Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention
title_full_unstemmed Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention
title_short Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention
title_sort complex interventions deserve complex evaluations: a transdisciplinary approach to evaluation of a preventive personalized medicine intervention
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854757/
https://www.ncbi.nlm.nih.gov/pubmed/35186838
http://dx.doi.org/10.3389/fpubh.2022.793137
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