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A Novel Humanized Anti-Abrin A Chain Antibody Inhibits Abrin Toxicity In Vitro and In Vivo
Abrin, a type-II ribosome inactivating protein from the seed of Abrus precatorius, is classified as a Category B bioterrorism warfare agent. Due to its high toxicity, ingestion by animals or humans will lead to death from multiple organ failure. Currently, no effective agents have been reported to t...
Autores principales: | Peng, Jingyi, Wu, Jiaguo, Shi, Ning, Xu, Hua, Luo, Longlong, Wang, Jing, Li, Xinying, Xiao, He, Feng, Jiannan, Li, Xia, Chai, Lihui, Qiao, Chunxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855095/ https://www.ncbi.nlm.nih.gov/pubmed/35185923 http://dx.doi.org/10.3389/fimmu.2022.831536 |
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