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Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation
Patients with inflammatory bowel disease (IBD) can develop extra-renal complications and as a result, suffer from end stage renal failure requiring kidney transplantation (KT). A brief review of available literature revealed that IBD patients undergoing KT have shorter overall survival rates compare...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Baishideng Publishing Group Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855143/ https://www.ncbi.nlm.nih.gov/pubmed/35211378 http://dx.doi.org/10.5500/wjt.v12.i2.21 |
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author | Singh, Urvashi Singh, Baljit Bellini, Maria Irene |
author_facet | Singh, Urvashi Singh, Baljit Bellini, Maria Irene |
author_sort | Singh, Urvashi |
collection | PubMed |
description | Patients with inflammatory bowel disease (IBD) can develop extra-renal complications and as a result, suffer from end stage renal failure requiring kidney transplantation (KT). A brief review of available literature revealed that IBD patients undergoing KT have shorter overall survival rates compared to their controls. Literature reporting steroid regimens and survival outcomes specific to IBD and post kidney transplant are scarce and these studies have small sample sizes thus making it difficult to draw accurate conclusions. Further research is required in the form of a randomized controlled study to clarify the effect and mechanism of steroid immunosuppression on the prognosis of renal transplant recipients and explore new treatment schemes. |
format | Online Article Text |
id | pubmed-8855143 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-88551432022-02-23 Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation Singh, Urvashi Singh, Baljit Bellini, Maria Irene World J Transplant Letter to the Editor Patients with inflammatory bowel disease (IBD) can develop extra-renal complications and as a result, suffer from end stage renal failure requiring kidney transplantation (KT). A brief review of available literature revealed that IBD patients undergoing KT have shorter overall survival rates compared to their controls. Literature reporting steroid regimens and survival outcomes specific to IBD and post kidney transplant are scarce and these studies have small sample sizes thus making it difficult to draw accurate conclusions. Further research is required in the form of a randomized controlled study to clarify the effect and mechanism of steroid immunosuppression on the prognosis of renal transplant recipients and explore new treatment schemes. Baishideng Publishing Group Inc 2022-02-18 2022-02-18 /pmc/articles/PMC8855143/ /pubmed/35211378 http://dx.doi.org/10.5500/wjt.v12.i2.21 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
spellingShingle | Letter to the Editor Singh, Urvashi Singh, Baljit Bellini, Maria Irene Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation |
title | Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation |
title_full | Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation |
title_fullStr | Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation |
title_full_unstemmed | Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation |
title_short | Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation |
title_sort | immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation |
topic | Letter to the Editor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855143/ https://www.ncbi.nlm.nih.gov/pubmed/35211378 http://dx.doi.org/10.5500/wjt.v12.i2.21 |
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