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Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation

Patients with inflammatory bowel disease (IBD) can develop extra-renal complications and as a result, suffer from end stage renal failure requiring kidney transplantation (KT). A brief review of available literature revealed that IBD patients undergoing KT have shorter overall survival rates compare...

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Autores principales: Singh, Urvashi, Singh, Baljit, Bellini, Maria Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855143/
https://www.ncbi.nlm.nih.gov/pubmed/35211378
http://dx.doi.org/10.5500/wjt.v12.i2.21
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author Singh, Urvashi
Singh, Baljit
Bellini, Maria Irene
author_facet Singh, Urvashi
Singh, Baljit
Bellini, Maria Irene
author_sort Singh, Urvashi
collection PubMed
description Patients with inflammatory bowel disease (IBD) can develop extra-renal complications and as a result, suffer from end stage renal failure requiring kidney transplantation (KT). A brief review of available literature revealed that IBD patients undergoing KT have shorter overall survival rates compared to their controls. Literature reporting steroid regimens and survival outcomes specific to IBD and post kidney transplant are scarce and these studies have small sample sizes thus making it difficult to draw accurate conclusions. Further research is required in the form of a randomized controlled study to clarify the effect and mechanism of steroid immunosuppression on the prognosis of renal transplant recipients and explore new treatment schemes.
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spelling pubmed-88551432022-02-23 Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation Singh, Urvashi Singh, Baljit Bellini, Maria Irene World J Transplant Letter to the Editor Patients with inflammatory bowel disease (IBD) can develop extra-renal complications and as a result, suffer from end stage renal failure requiring kidney transplantation (KT). A brief review of available literature revealed that IBD patients undergoing KT have shorter overall survival rates compared to their controls. Literature reporting steroid regimens and survival outcomes specific to IBD and post kidney transplant are scarce and these studies have small sample sizes thus making it difficult to draw accurate conclusions. Further research is required in the form of a randomized controlled study to clarify the effect and mechanism of steroid immunosuppression on the prognosis of renal transplant recipients and explore new treatment schemes. Baishideng Publishing Group Inc 2022-02-18 2022-02-18 /pmc/articles/PMC8855143/ /pubmed/35211378 http://dx.doi.org/10.5500/wjt.v12.i2.21 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Letter to the Editor
Singh, Urvashi
Singh, Baljit
Bellini, Maria Irene
Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation
title Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation
title_full Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation
title_fullStr Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation
title_full_unstemmed Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation
title_short Immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation
title_sort immunosuppressive regimens and outcomes of inflammatory bowel disease patients requiring kidney transplantation
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855143/
https://www.ncbi.nlm.nih.gov/pubmed/35211378
http://dx.doi.org/10.5500/wjt.v12.i2.21
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