Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant

Histone H3mm18 is a non-allelic H3 variant expressed in skeletal muscle and brain in mice. However, its function has remained enigmatic. We found that H3mm18 is incorporated into chromatin in cells with low efficiency, as compared to H3.3. We determined the structures of the nucleosome core particle...

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Detalles Bibliográficos
Autores principales: Hirai, Seiya, Tomimatsu, Kosuke, Miyawaki-Kuwakado, Atsuko, Takizawa, Yoshimasa, Komatsu, Tetsuro, Tachibana, Taro, Fukushima, Yutaro, Takeda, Yasuko, Negishi, Lumi, Kujirai, Tomoya, Koyama, Masako, Ohkawa, Yasuyuki, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855299/
https://www.ncbi.nlm.nih.gov/pubmed/34929737
http://dx.doi.org/10.1093/nar/gkab1137

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