Lovastatin Inhibits RhoA to Suppress Canonical Wnt/β-Catenin Signaling and Alternative Wnt-YAP/TAZ Signaling in Colon Cancer

Statins are first-line drugs used to control patient lipid levels, but there is recent evidence that statin treatment can lower colorectal cancer (CRC) incidence by 50% and prolong CRC patient survival through mechanisms that are poorly understood. In this study, we found that the treatment of APC(m...

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Detalles Bibliográficos
Autores principales: Xiao, Yi, Liu, Qin, Peng, Nanyin, Li, Yuzhang, Qiu, Danyang, Yang, Tianlun, Kang, Richard, Usmani, Ahsan, Amadasu, Efosa, Borlongan, Cesario V., Yu, Guolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855423/
https://www.ncbi.nlm.nih.gov/pubmed/35168393
http://dx.doi.org/10.1177/09636897221075749

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