Pluripotency exit is guided by the Peln1-mediated disruption of intrachromosomal architecture

The molecular circuitry that causes stem cells to exit from pluripotency remains largely uncharacterized. Using chromatin RNA in situ reverse transcription sequencing, we identified Peln1 as a novel chromatin RNA component in the promoter complex of Oct4, a stem cell master transcription factor gene...

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Detalles Bibliográficos
Autores principales: Wang, Yichen, Jia, Lin, Wang, Cong, Du, Zhonghua, Zhang, Shilin, Zhou, Lei, Wen, Xue, Li, Hui, Chen, Huiling, Nie, Yuanyuan, Li, Dan, Liu, Shanshan, Figueroa, Daniela Salgado, Ay, Ferhat, Xu, Wei, Zhang, Songling, Li, Wei, Cui, Jiuwei, Hoffman, Andrew R., Guo, Hui, Hu, Ji-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855478/
https://www.ncbi.nlm.nih.gov/pubmed/35171230
http://dx.doi.org/10.1083/jcb.202009134

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