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Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection

Cytomegalovirus (CMV) increases tuberculosis (TB) risk, but its relationship with latent TB infection (LTBI) is unknown. Using US nationally representative data, we report that CMV was independently associated with LTBI (odds ratio, 2.94; 95% CI, 1.19–7.28; P=.02). CMV and LTBI were associated with...

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Detalles Bibliográficos
Autores principales: van der Heijden, Yuri F, Zhang, Bin, Chougnet, Claire A, Huaman, Moises A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855520/
https://www.ncbi.nlm.nih.gov/pubmed/35198641
http://dx.doi.org/10.1093/ofid/ofab539
Descripción
Sumario:Cytomegalovirus (CMV) increases tuberculosis (TB) risk, but its relationship with latent TB infection (LTBI) is unknown. Using US nationally representative data, we report that CMV was independently associated with LTBI (odds ratio, 2.94; 95% CI, 1.19–7.28; P=.02). CMV and LTBI were associated with higher C-reactive protein, suggesting chronic inflammation.