Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection

Cytomegalovirus (CMV) increases tuberculosis (TB) risk, but its relationship with latent TB infection (LTBI) is unknown. Using US nationally representative data, we report that CMV was independently associated with LTBI (odds ratio, 2.94; 95% CI, 1.19–7.28; P=.02). CMV and LTBI were associated with...

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Autores principales: van der Heijden, Yuri F, Zhang, Bin, Chougnet, Claire A, Huaman, Moises A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855520/
https://www.ncbi.nlm.nih.gov/pubmed/35198641
http://dx.doi.org/10.1093/ofid/ofab539
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author van der Heijden, Yuri F
Zhang, Bin
Chougnet, Claire A
Huaman, Moises A
author_facet van der Heijden, Yuri F
Zhang, Bin
Chougnet, Claire A
Huaman, Moises A
author_sort van der Heijden, Yuri F
collection PubMed
description Cytomegalovirus (CMV) increases tuberculosis (TB) risk, but its relationship with latent TB infection (LTBI) is unknown. Using US nationally representative data, we report that CMV was independently associated with LTBI (odds ratio, 2.94; 95% CI, 1.19–7.28; P=.02). CMV and LTBI were associated with higher C-reactive protein, suggesting chronic inflammation.
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spelling pubmed-88555202022-02-22 Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection van der Heijden, Yuri F Zhang, Bin Chougnet, Claire A Huaman, Moises A Open Forum Infect Dis Brief Reports Cytomegalovirus (CMV) increases tuberculosis (TB) risk, but its relationship with latent TB infection (LTBI) is unknown. Using US nationally representative data, we report that CMV was independently associated with LTBI (odds ratio, 2.94; 95% CI, 1.19–7.28; P=.02). CMV and LTBI were associated with higher C-reactive protein, suggesting chronic inflammation. Oxford University Press 2021-10-23 /pmc/articles/PMC8855520/ /pubmed/35198641 http://dx.doi.org/10.1093/ofid/ofab539 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
van der Heijden, Yuri F
Zhang, Bin
Chougnet, Claire A
Huaman, Moises A
Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection
title Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection
title_full Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection
title_fullStr Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection
title_full_unstemmed Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection
title_short Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection
title_sort cytomegalovirus infection is associated with increased prevalence of latent tuberculosis infection
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855520/
https://www.ncbi.nlm.nih.gov/pubmed/35198641
http://dx.doi.org/10.1093/ofid/ofab539
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