Clinico-histopathologic and single-nuclei RNA-sequencing insights into cardiac injury and microthrombi in critical COVID-19

Acute cardiac injury is prevalent in critical COVID-19 and associated with increased mortality. Its etiology remains debated, as initially presumed causes — myocarditis and cardiac necrosis — have proved uncommon. To elucidate the pathophysiology of COVID-19–associated cardiac injury, we conducted a...

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Detalles Bibliográficos
Autores principales: Brener, Michael I., Hulke, Michelle L., Fukuma, Nobuaki, Golob, Stephanie, Zilinyi, Robert S., Zhou, Zhipeng, Tzimas, Christos, Russo, Ilaria, McGroder, Claire, Pfeiffer, Ryan D., Chong, Alexander, Zhang, Geping, Burkhoff, Daniel, Leon, Martin B., Maurer, Mathew S., Moses, Jeffrey W., Uhlemann, Anne-Catrin, Hibshoosh, Hanina, Uriel, Nir, Szabolcs, Matthias J., Redfors, Björn, Marboe, Charles C., Baldwin, Matthew R., Tucker, Nathan R., Tsai, Emily J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855793/
https://www.ncbi.nlm.nih.gov/pubmed/34905515
http://dx.doi.org/10.1172/jci.insight.154633

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