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Differential localization and limited cytotoxic potential of duodenal CD8(+) T cells

The duodenum is a major site of HIV persistence during suppressive antiretroviral therapy despite harboring abundant tissue-resident memory (Trm) CD8(+) T cells. The role of duodenal Trm CD8(+) T cells in viral control is still not well defined. We examined the spatial localization, phenotype, and f...

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Detalles Bibliográficos
Autores principales:	Mvaya, Leonard, Khaba, Trevor, Lakudzala, Agness E., Nkosi, Thandeka, Jambo, Ndaru, Kadwala, Innocent, Kankwatira, Anstead, Patel, Priyanka D., Gordon, Melita A., Nyirenda, Tonney S., Jambo, Kondwani C., Ndhlovu, Zaza M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855799/ https://www.ncbi.nlm.nih.gov/pubmed/35132966 http://dx.doi.org/10.1172/jci.insight.154195

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