ADAM8 signaling drives neutrophil migration and ARDS severity

Acute respiratory distress syndrome (ARDS) results in catastrophic lung failure and has an urgent, unmet need for improved early recognition and therapeutic development. Neutrophil influx is a hallmark of ARDS and is associated with the release of tissue-destructive immune effectors, such as matrix...

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Detalles Bibliográficos
Autores principales: Conrad, Catharina, Yildiz, Daniela, Cleary, Simon J., Margraf, Andreas, Cook, Lena, Schlomann, Uwe, Panaretou, Barry, Bowser, Jessica L., Karmouty-Quintana, Harry, Li, Jiwen, Berg, Nathaniel K., Martin, Samuel C., Aljohmani, Ahmad, Moussavi-Harami, S. Farshid, Wang, Kristin M., Tian, Jennifer J., Magnen, Mélia, Valet, Colin, Qiu, Longhui, Singer, Jonathan P., Eltzschig, Holger K., Bertrams, Wilhelm, Herold, Susanne, Suttorp, Norbert, Schmeck, Bernd, Ball, Zachary T., Zarbock, Alexander, Looney, Mark R., Bartsch, Jörg W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855804/
https://www.ncbi.nlm.nih.gov/pubmed/35132956
http://dx.doi.org/10.1172/jci.insight.149870

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