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Tissue metabolites in diffuse glioma and their modulations by IDH1 mutation, histology, and treatment

The discovery of the oncometabolite 2-hydroxyglutarate in isocitrate dehydrogenase 1–mutated (IDH1-mutated) tumor entities affirmed the role of metabolism in cancer. However, large databases with tissue metabolites that are modulated by IDH1 mutation remain an area of development. Here, we present a...

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Detalles Bibliográficos
Autores principales: Trautwein, Christoph, Zizmare, Laimdota, Mäurer, Irina, Bender, Benjamin, Bayer, Björn, Ernemann, Ulrike, Tatagiba, Marcos, Grau, Stefan J., Pichler, Bernd J., Skardelly, Marco, Tabatabai, Ghazaleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855807/
https://www.ncbi.nlm.nih.gov/pubmed/34941573
http://dx.doi.org/10.1172/jci.insight.153526