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The RNA-binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammation

Stromal cells are emerging as key drivers of autoimmunity, partially because they produce inflammatory chemokines that orchestrate inflammation. Chemokine expression is regulated transcriptionally but also through posttranscriptional mechanisms, the specific drivers of which are still incompletely d...

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Detalles Bibliográficos
Autores principales: Bechara, Rami, Amatya, Nilesh, Majumder, Saikat, Zhou, Chunsheng, Li, Yang, Liu, Qixing, McGeachy, Mandy J., Gaffen, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855811/
https://www.ncbi.nlm.nih.gov/pubmed/34914635
http://dx.doi.org/10.1172/jci.insight.152766