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Anticachectic regulator analysis reveals Perp-dependent antitumorigenic properties of 3-methyladenine in pancreatic cancer

Approximately 80% of pancreatic cancer patients suffer from cachexia, and one-third die due to cachexia-related complications such as respiratory failure and cardiac arrest. Although there has been considerable research into cachexia mechanisms and interventions, there are, to date, no FDA-approved...

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Detalles Bibliográficos
Autores principales:	Dasgupta, Aneesha, Arneson-Wissink, Paige C., Schmitt, Rebecca E., Cho, Dong Seong, Ducharme, Alexandra M., Hogenson, Tara L., Krueger, Eugene W., Bamlet, William R., Zhang, Lizhi, Razidlo, Gina L., Fernandez-Zapico, Martin E., Doles, Jason D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855816/ https://www.ncbi.nlm.nih.gov/pubmed/34874916 http://dx.doi.org/10.1172/jci.insight.153842

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