Nrf2 regulates downstream genes by targeting miR-29b in severe asthma and the role of grape seed proanthocyanidin extract in a murine model of steroid-insensitive asthma

CONTEXT: Grape seed proanthocyanidin extract (GSPE) is effective in treating severe asthma (SA). OBJECTIVE: To examine the relationship between Nrf2-miR-29b axis and SA, and to detect whether preventive use of GSPE relieves SA via it. MATERIALS AND METHODS: We recruited 10 healthy controls, 10 patie...

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Detalles Bibliográficos
Autores principales: Qian, Yan, Sun, Yun, Chen, Yi, Mao, Zhengdao, Shi, Yujia, Wu, Di, Gu, Bin, Liu, Zhiguang, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856085/
https://www.ncbi.nlm.nih.gov/pubmed/35171066
http://dx.doi.org/10.1080/13880209.2022.2032205

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