Mycobacterium marinum Infection and Interferon-Gamma Release Assays Cross-Reactivity: A Case Report

Mycobacterium marinum (M. marinum) is a pathogen that causes skin and soft tissue infections in people who work with contaminated water, such as fish handlers. M. marinum infection is mostly limited to patients with compromised immune systems. As per current guidelines, susceptibility testing is not...

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Autores principales: Patel, Premalkumar M, Camps, Nicholas, Rivera, Cynthia I, Tuda, Claudio, VanOstran, Garrett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856640/
https://www.ncbi.nlm.nih.gov/pubmed/35198325
http://dx.doi.org/10.7759/cureus.21420
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author Patel, Premalkumar M
Camps, Nicholas
Rivera, Cynthia I
Tuda, Claudio
VanOstran, Garrett
author_facet Patel, Premalkumar M
Camps, Nicholas
Rivera, Cynthia I
Tuda, Claudio
VanOstran, Garrett
author_sort Patel, Premalkumar M
collection PubMed
description Mycobacterium marinum (M. marinum) is a pathogen that causes skin and soft tissue infections in people who work with contaminated water, such as fish handlers. M. marinum infection is mostly limited to patients with compromised immune systems. As per current guidelines, susceptibility testing is not routinely recommended(,) although sporadic cases have been reported with resistance to routinely prescribed anti-tuberculous drugs. We report a case of a 61-year-old male taking adalimumab with ulcerative skin and soft tissue infection with positive interferon-gamma release assays (IGRA) identified as M. marinum and the treatment challenges involved in this case.
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spelling pubmed-88566402022-02-22 Mycobacterium marinum Infection and Interferon-Gamma Release Assays Cross-Reactivity: A Case Report Patel, Premalkumar M Camps, Nicholas Rivera, Cynthia I Tuda, Claudio VanOstran, Garrett Cureus Infectious Disease Mycobacterium marinum (M. marinum) is a pathogen that causes skin and soft tissue infections in people who work with contaminated water, such as fish handlers. M. marinum infection is mostly limited to patients with compromised immune systems. As per current guidelines, susceptibility testing is not routinely recommended(,) although sporadic cases have been reported with resistance to routinely prescribed anti-tuberculous drugs. We report a case of a 61-year-old male taking adalimumab with ulcerative skin and soft tissue infection with positive interferon-gamma release assays (IGRA) identified as M. marinum and the treatment challenges involved in this case. Cureus 2022-01-19 /pmc/articles/PMC8856640/ /pubmed/35198325 http://dx.doi.org/10.7759/cureus.21420 Text en Copyright © 2022, Patel et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Infectious Disease
Patel, Premalkumar M
Camps, Nicholas
Rivera, Cynthia I
Tuda, Claudio
VanOstran, Garrett
Mycobacterium marinum Infection and Interferon-Gamma Release Assays Cross-Reactivity: A Case Report
title Mycobacterium marinum Infection and Interferon-Gamma Release Assays Cross-Reactivity: A Case Report
title_full Mycobacterium marinum Infection and Interferon-Gamma Release Assays Cross-Reactivity: A Case Report
title_fullStr Mycobacterium marinum Infection and Interferon-Gamma Release Assays Cross-Reactivity: A Case Report
title_full_unstemmed Mycobacterium marinum Infection and Interferon-Gamma Release Assays Cross-Reactivity: A Case Report
title_short Mycobacterium marinum Infection and Interferon-Gamma Release Assays Cross-Reactivity: A Case Report
title_sort mycobacterium marinum infection and interferon-gamma release assays cross-reactivity: a case report
topic Infectious Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856640/
https://www.ncbi.nlm.nih.gov/pubmed/35198325
http://dx.doi.org/10.7759/cureus.21420
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