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Cannabidiol activates neuronal Kv7 channels
Cannabidiol (CBD), a chemical found in the Cannabis sativa plant, is a clinically effective antiepileptic drug whose mechanism of action is unknown. Using a fluorescence-based thallium flux assay, we performed a large-scale screen and found enhancement of flux through heterologously expressed human...
Autores principales: | Zhang, Han-Xiong Bear, Heckman, Laurel, Niday, Zachary, Jo, Sooyeon, Fujita, Akie, Shim, Jaehoon, Pandey, Roshan, Al Jandal, Hoor, Jayakar, Selwyn, Barrett, Lee B, Smith, Jennifer, Woolf, Clifford J, Bean, Bruce P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856652/ https://www.ncbi.nlm.nih.gov/pubmed/35179483 http://dx.doi.org/10.7554/eLife.73246 |
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