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MRI Stereoscope: A Miniature Stereoscope for Human Neuroimaging

Stereoscopic vision enables the perception of depth. To study the brain mechanisms behind stereoscopic vision using noninvasive brain imaging (magnetic resonance brain imaging; MRI), scientists need to reproduce the independent views of the left and right eyes in the brain scanner using “dichoptic”...

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Autores principales: Ip, I. Betina, Alvarez, Ivan, Tacon, Mike, Parker, Andrew J., Bridge, Holly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856700/
https://www.ncbi.nlm.nih.gov/pubmed/35045974
http://dx.doi.org/10.1523/ENEURO.0382-21.2021
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author Ip, I. Betina
Alvarez, Ivan
Tacon, Mike
Parker, Andrew J.
Bridge, Holly
author_facet Ip, I. Betina
Alvarez, Ivan
Tacon, Mike
Parker, Andrew J.
Bridge, Holly
author_sort Ip, I. Betina
collection PubMed
description Stereoscopic vision enables the perception of depth. To study the brain mechanisms behind stereoscopic vision using noninvasive brain imaging (magnetic resonance brain imaging; MRI), scientists need to reproduce the independent views of the left and right eyes in the brain scanner using “dichoptic” displays. However, high-quality dichoptic displays are technically challenging and costly to implement in the MRI scanner. The novel miniature stereoscope system (“MRI stereoscope”) is an affordable and open-source tool that displays high-quality dichoptic images inside the MRI scanner. The MRI stereoscope takes advantage of commonly used display equipment, the MRI head coil, and a display screen. To validate the MRI stereoscope, binocular disparity stimuli were presented in a 3T MRI scanner while neural activation was recorded using functional MRI in six human participants. The comparison of large binocular disparities compared with disparities close to zero evoked strong responses across dorsal and ventral extra-striate visual cortex. In contrast, binocularly anti-correlated stimuli, which are not perceived in depth, did not evoke comparable activation. These results are the proof-of-concept that the MRI stereoscope can deliver dichoptic images that produce the perception of stereoscopic depth during acquisition of MR responses. Application of the MRI stereoscope to neuroscience can help to address important questions in perception and consciousness.
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spelling pubmed-88567002022-02-22 MRI Stereoscope: A Miniature Stereoscope for Human Neuroimaging Ip, I. Betina Alvarez, Ivan Tacon, Mike Parker, Andrew J. Bridge, Holly eNeuro Open Source Tools and Methods Stereoscopic vision enables the perception of depth. To study the brain mechanisms behind stereoscopic vision using noninvasive brain imaging (magnetic resonance brain imaging; MRI), scientists need to reproduce the independent views of the left and right eyes in the brain scanner using “dichoptic” displays. However, high-quality dichoptic displays are technically challenging and costly to implement in the MRI scanner. The novel miniature stereoscope system (“MRI stereoscope”) is an affordable and open-source tool that displays high-quality dichoptic images inside the MRI scanner. The MRI stereoscope takes advantage of commonly used display equipment, the MRI head coil, and a display screen. To validate the MRI stereoscope, binocular disparity stimuli were presented in a 3T MRI scanner while neural activation was recorded using functional MRI in six human participants. The comparison of large binocular disparities compared with disparities close to zero evoked strong responses across dorsal and ventral extra-striate visual cortex. In contrast, binocularly anti-correlated stimuli, which are not perceived in depth, did not evoke comparable activation. These results are the proof-of-concept that the MRI stereoscope can deliver dichoptic images that produce the perception of stereoscopic depth during acquisition of MR responses. Application of the MRI stereoscope to neuroscience can help to address important questions in perception and consciousness. Society for Neuroscience 2022-02-14 /pmc/articles/PMC8856700/ /pubmed/35045974 http://dx.doi.org/10.1523/ENEURO.0382-21.2021 Text en Copyright © 2022 Ip et al. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Open Source Tools and Methods
Ip, I. Betina
Alvarez, Ivan
Tacon, Mike
Parker, Andrew J.
Bridge, Holly
MRI Stereoscope: A Miniature Stereoscope for Human Neuroimaging
title MRI Stereoscope: A Miniature Stereoscope for Human Neuroimaging
title_full MRI Stereoscope: A Miniature Stereoscope for Human Neuroimaging
title_fullStr MRI Stereoscope: A Miniature Stereoscope for Human Neuroimaging
title_full_unstemmed MRI Stereoscope: A Miniature Stereoscope for Human Neuroimaging
title_short MRI Stereoscope: A Miniature Stereoscope for Human Neuroimaging
title_sort mri stereoscope: a miniature stereoscope for human neuroimaging
topic Open Source Tools and Methods
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856700/
https://www.ncbi.nlm.nih.gov/pubmed/35045974
http://dx.doi.org/10.1523/ENEURO.0382-21.2021
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