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The Ecto-5′nucleotidase/CD73 Mediates Leishmania amazonensis Survival in Macrophages

Endogenous nucleotides produced by various group of cells under inflammatory conditions act as potential danger signals in vivo. Extracellularly released nucleotides such as ATP are rapidly hydrolyzed to adenosine by the coordinated ectonucleotidase activities of CD39 and CD73. Leishmania is an obli...

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Detalles Bibliográficos
Autores principales: Bajracharya, Bijay, Shrestha, Deena, Talvani, André, Gonçalves, Ricardo, Afonso, Luís Carlos Crocco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856795/
https://www.ncbi.nlm.nih.gov/pubmed/35187176
http://dx.doi.org/10.1155/2022/9928362