Cargando…
Research on the Damage of Adrenal Pheochromocytoma to Patients' Cardiovascular Vessels and Its Correlation with Hypertension
Chromaffin cell-centered pheochromocytoma (Pheo) is a rare tumour. Pheochromocytoma and how it affects the heart will be the topic of this article. Due to the comparable symptoms and indications of the sympathetic nervous system, a pheochromocytoma might be difficult to detect early. There are also...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856813/ https://www.ncbi.nlm.nih.gov/pubmed/35186079 http://dx.doi.org/10.1155/2022/3644212 |
_version_ | 1784653921662271488 |
---|---|
author | Wang, Xiaohui Zhao, Qiuping Sang, Haiqiang Dong, Jiajia Bai, Minfu |
author_facet | Wang, Xiaohui Zhao, Qiuping Sang, Haiqiang Dong, Jiajia Bai, Minfu |
author_sort | Wang, Xiaohui |
collection | PubMed |
description | Chromaffin cell-centered pheochromocytoma (Pheo) is a rare tumour. Pheochromocytoma and how it affects the heart will be the topic of this article. Due to the comparable symptoms and indications of the sympathetic nervous system, a pheochromocytoma might be difficult to detect early. There are also other frequent differential diagnoses that might delay the detection of a pheochromocytoma. One of the most common side effects of pheochromocytoma is unmanageable hypertension. Hypertensive crisis (extreme increases in blood pressure) can develop, which is a life-threatening condition that leads to strokes or arrhythmia. Estimated to affect African Americans significantly, they frequently go undetected due to a lack of resources or accessibility of services. Because this tumour is difficult to identify and its symptoms often resemble those of other diseases, it is frequently overlooked. A pheochromocytoma's long-term consequences can include cardiac muscle deterioration, congestive heart failure (CHF), a higher diabetes risk and possibly death. Masked hypertension (MH) is more common in people with adrenal pheochromocytoma, which has been related to an increased risk of heart disease. With the use of ambulatory blood pressure monitoring, this research set out to find out how common mental health issues are among people with APs. There were 85 participants in all, 43 of whom had APs and 42 of whom had the same age, gender, BMI, smoking and diabetes as the AP patients. Measurements were made of the BP and AP in both the diseased and control groups. Retrospective data collection was used to gather biochemical, hormonal and radiological information on the patients. The Pearson–Boltzmann CNN method was then used to assess risk based on the diagnosis results. Furthermore, depending on the risk score, more nonselective blockers (e.g., prazosin, doxazosin, terazosin, and metyrosine) have been used to lower perioperative catecholamine levels, hence reducing illness risk. After a successful surgical excision of the tumour, the recommended therapy can usually be stopped quickly. |
format | Online Article Text |
id | pubmed-8856813 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-88568132022-02-19 Research on the Damage of Adrenal Pheochromocytoma to Patients' Cardiovascular Vessels and Its Correlation with Hypertension Wang, Xiaohui Zhao, Qiuping Sang, Haiqiang Dong, Jiajia Bai, Minfu J Oncol Research Article Chromaffin cell-centered pheochromocytoma (Pheo) is a rare tumour. Pheochromocytoma and how it affects the heart will be the topic of this article. Due to the comparable symptoms and indications of the sympathetic nervous system, a pheochromocytoma might be difficult to detect early. There are also other frequent differential diagnoses that might delay the detection of a pheochromocytoma. One of the most common side effects of pheochromocytoma is unmanageable hypertension. Hypertensive crisis (extreme increases in blood pressure) can develop, which is a life-threatening condition that leads to strokes or arrhythmia. Estimated to affect African Americans significantly, they frequently go undetected due to a lack of resources or accessibility of services. Because this tumour is difficult to identify and its symptoms often resemble those of other diseases, it is frequently overlooked. A pheochromocytoma's long-term consequences can include cardiac muscle deterioration, congestive heart failure (CHF), a higher diabetes risk and possibly death. Masked hypertension (MH) is more common in people with adrenal pheochromocytoma, which has been related to an increased risk of heart disease. With the use of ambulatory blood pressure monitoring, this research set out to find out how common mental health issues are among people with APs. There were 85 participants in all, 43 of whom had APs and 42 of whom had the same age, gender, BMI, smoking and diabetes as the AP patients. Measurements were made of the BP and AP in both the diseased and control groups. Retrospective data collection was used to gather biochemical, hormonal and radiological information on the patients. The Pearson–Boltzmann CNN method was then used to assess risk based on the diagnosis results. Furthermore, depending on the risk score, more nonselective blockers (e.g., prazosin, doxazosin, terazosin, and metyrosine) have been used to lower perioperative catecholamine levels, hence reducing illness risk. After a successful surgical excision of the tumour, the recommended therapy can usually be stopped quickly. Hindawi 2022-02-11 /pmc/articles/PMC8856813/ /pubmed/35186079 http://dx.doi.org/10.1155/2022/3644212 Text en Copyright © 2022 Xiaohui Wang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Wang, Xiaohui Zhao, Qiuping Sang, Haiqiang Dong, Jiajia Bai, Minfu Research on the Damage of Adrenal Pheochromocytoma to Patients' Cardiovascular Vessels and Its Correlation with Hypertension |
title | Research on the Damage of Adrenal Pheochromocytoma to Patients' Cardiovascular Vessels and Its Correlation with Hypertension |
title_full | Research on the Damage of Adrenal Pheochromocytoma to Patients' Cardiovascular Vessels and Its Correlation with Hypertension |
title_fullStr | Research on the Damage of Adrenal Pheochromocytoma to Patients' Cardiovascular Vessels and Its Correlation with Hypertension |
title_full_unstemmed | Research on the Damage of Adrenal Pheochromocytoma to Patients' Cardiovascular Vessels and Its Correlation with Hypertension |
title_short | Research on the Damage of Adrenal Pheochromocytoma to Patients' Cardiovascular Vessels and Its Correlation with Hypertension |
title_sort | research on the damage of adrenal pheochromocytoma to patients' cardiovascular vessels and its correlation with hypertension |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856813/ https://www.ncbi.nlm.nih.gov/pubmed/35186079 http://dx.doi.org/10.1155/2022/3644212 |
work_keys_str_mv | AT wangxiaohui researchonthedamageofadrenalpheochromocytomatopatientscardiovascularvesselsanditscorrelationwithhypertension AT zhaoqiuping researchonthedamageofadrenalpheochromocytomatopatientscardiovascularvesselsanditscorrelationwithhypertension AT sanghaiqiang researchonthedamageofadrenalpheochromocytomatopatientscardiovascularvesselsanditscorrelationwithhypertension AT dongjiajia researchonthedamageofadrenalpheochromocytomatopatientscardiovascularvesselsanditscorrelationwithhypertension AT baiminfu researchonthedamageofadrenalpheochromocytomatopatientscardiovascularvesselsanditscorrelationwithhypertension |