Cargando…

PTPN6-EGFR Protein Complex: A Novel Target for Colon Cancer Metastasis

This study investigates the expression of nonreceptor protein tyrosine phosphatase 6 (PTPN6) gene in different colon cancer cells and its effect on malignant biological behavior. The expression level of PTPN6 mRNA in different colon cancer cell lines was detected by qPCR. CCK-8, clone formation assa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Gang, Zhang, Yan, Huang, Yun, Yuan, Xinpu, Cao, Zhen, Zhao, Zhanwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856819/ https://www.ncbi.nlm.nih.gov/pubmed/35186080 http://dx.doi.org/10.1155/2022/7391069

Ejemplares similares

Novel Potential Therapeutic Targets of PTPN Families for Lung Cancer
por: Wang, Chin-Chou, et al.
Publicado: (2022)

Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses
por: Ventura, Pedro M O, et al.
Publicado: (2022)

Safety and feasibility of total laparoscopic radical resection of Siewert type II gastroesophageal junction adenocarcinoma through the left diaphragm and left thoracic auxiliary hole
por: Huang, Yun, et al.
Publicado: (2021)

Total laparoscopic transabdominal-transdiaphragmatic approach for treating Siewert II tumors: a prospective analysis of a case series
por: Pang, Wei, et al.
Publicado: (2021)

PTPN22.6, a Dominant Negative Isoform of PTPN22 and Potential Biomarker of Rheumatoid Arthritis
por: Chang, Hui-Hsin, et al.
Publicado: (2012)

PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis
por: Hsieh, Wan-Chen, et al.
Publicado: (2020)

PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target
por: Singh, Shaifali, et al.
Publicado: (2023)

Autoimmunity linked protein phosphatase PTPN22 as a target for cancer immunotherapy
por: Cubas, Rafael, et al.
Publicado: (2020)

Protein tyrosine phosphatase nonreceptor 13 (PTPN13) is targeted by human papillomavirus 16 E6 in cervical epithelium
por: Nowicki, P, et al.
Publicado: (2009)

PTPN2 as a promoter of colon carcinoma via reduction of inflammasome activation
por: Spalinger, Marianne R., et al.
Publicado: (2018)

High-Risk Human Papillomavirus E7 Proteins Target PTPN14 for Degradation
por: White, Elizabeth A., et al.
Publicado: (2016)

The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens
por: Clarke, Fiona, et al.
Publicado: (2018)

Comprehensive analysis of PTPN gene family revealing PTPN7 as a novel biomarker for immuno-hot tumors in breast cancer
por: Wang, Fengxu, et al.
Publicado: (2022)

The Analysis of PTPN6 for Bladder Cancer: An Exploratory Study Based on TCGA
por: Shen, Chengquan, et al.
Publicado: (2020)

Redoxing PTPN22 activity
por: Shumanska, Magdalena, et al.
Publicado: (2022)

The FERM and PDZ Domain-Containing Protein Tyrosine Phosphatases, PTPN4 and PTPN3, Are Both Dispensable for T Cell Receptor Signal Transduction
por: Bauler, Timothy J., et al.
Publicado: (2008)

Curcumin inhibits proliferation of hepatocellular carcinoma cells by blocking PTPN1 and PTPN11 expression
por: Zhang, Jingru, et al.
Publicado: (2023)

Ethyl Gallate Dual-Targeting PTPN6 and PPARγ Shows Anti-Diabetic and Anti-Obese Effects
por: Ahn, Dohee, et al.
Publicado: (2022)

The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization
por: Husedzinovic, Alma, et al.
Publicado: (2015)

Silibinin Inhibits NSCLC Metastasis by Targeting the EGFR/LOX Pathway
por: Hou, Xiaoying, et al.
Publicado: (2018)

Decreased Expression of PTPN12 Correlates with Tumor Recurrence and Poor Survival of Patients with Hepatocellular Carcinoma
por: Luo, Rong-Zhen, et al.
Publicado: (2014)

PTPN2 negatively regulates macrophage inflammation in atherosclerosis
por: Hu, Xiaorong, et al.
Publicado: (2020)

Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation
por: Speir, Mary, et al.
Publicado: (2019)

Genetic Variations of PTPN2 and PTPN22: Role in the Pathogenesis of Type 1 Diabetes and Crohn's Disease
por: Sharp, Robert C., et al.
Publicado: (2015)

The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity
por: Baumgartner, Christina K., et al.
Publicado: (2023)

Protein Tyrosine Phosphatase SHP-2 (PTPN11) in Hematopoiesis and Leukemogenesis
por: Liu, Xia, et al.
Publicado: (2011)

Clinicopathological significance of PTPN12 expression in human breast cancer
por: Yuan, Xunyi, et al.
Publicado: (2012)

Nuclear import of PTPN18 inhibits breast cancer metastasis mediated by MVP and importin β2
por: Wang, Tao, et al.
Publicado: (2022)

CD47 halts Ptpn6-deficient neutrophils from provoking lethal inflammation
por: Mazgaeen, Lalita, et al.
Publicado: (2023)

Novel missense mutation in PTPN22 in a Chinese pedigree with Hashimoto’s thyroiditis
por: Gong, Licheng, et al.
Publicado: (2018)

Noonan syndrome: rhGH treatment and PTPN11 mutation
por: Wu, Xian, et al.
Publicado: (2023)

PTPN2, A Key Predictor of Prognosis for Pancreatic Adenocarcinoma, Significantly Regulates Cell Cycles, Apoptosis, and Metastasis
por: Kuang, Wenbin, et al.
Publicado: (2022)

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
por: Spalinger, Marianne R., et al.
Publicado: (2023)

Modeling the effect of PTPN22 in rheumatoid arthritis
por: Bourgey, Mathieu, et al.
Publicado: (2007)

Hepatocyte-Specific Ptpn6 Deletion Protects From Obesity-Linked Hepatic Insulin Resistance
por: Xu, Elaine, et al.
Publicado: (2012)

Single-cell and bulk sequencing analyses reveal the immune suppressive role of PTPN6 in glioblastoma
por: Zhang, Xiaonan, et al.
Publicado: (2023)

pTyr(421) Cortactin Is Overexpressed in Colon Cancer and Is Dephosphorylated by Curcumin: Involvement of Non-Receptor Type 1 Protein Tyrosine Phosphatase (PTPN1)
por: Radhakrishnan, Vijayababu M., et al.
Publicado: (2014)

A Novel A461S Mutation of PTPN11 in a Female with LEOPARD Syndrome
por: Yoshida, Rie, et al.
Publicado: (2008)

PTPN21/Pez Is a Novel and Evolutionarily Conserved Key Regulator of Inflammation In Vivo
por: Campbell, Jennie S., et al.
Publicado: (2021)

LEPOARD syndrome: A report of a case with a novel PTPN11 mutation
por: Rahal, Nader, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_plg0miit5u1edjqgf4o31nbfjo