MiR-138 is a potent regulator of the heterogenous MYC transcript population in cancers

3′UTR shortening in cancer has been shown to activate oncogenes, partly through the loss of microRNA-mediated repression. This suggests that many reported microRNA-oncogene target interactions may not be present in cancer cells. One of the most well-studied oncogenes is the transcription factor MYC,...

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Detalles Bibliográficos
Autores principales: Desi, Ng, Teh, Velda, Tong, Qing Yun, Lim, Chun You, Tabatabaeian, Hossein, Chew, Xiao Hong, Sanchez-Mejias, Avencia, Chan, Jia Jia, Zhang, Bin, Pitcheshwar, Priyankaa, Siew, Bei-En, Wang, Shi, Lee, Kuok-Chung, Chong, Choon-Seng, Cheong, Wai-Kit, Lieske, Bettina, Tan, Ian Jse-Wei, Tan, Ker-Kan, Tay, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856960/
https://www.ncbi.nlm.nih.gov/pubmed/34937878
http://dx.doi.org/10.1038/s41388-021-02084-x

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