Afidopyropen, a novel insecticide originating from microbial secondary extracts

Afidopyropen, a novel insecticide, is a derivative of pyripyropene A, which is produced by the filamentous fungus Penicillium coprobium. Afidopyropen has strong insecticidal activity against aphids and is currently used as a control agent of sucking pests worldwide. In this study, we summarized the...

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Autores principales: Horikoshi, Ryo, Goto, Kimihiko, Mitomi, Masaaki, Oyama, Kazuhiko, Hirose, Tomoyasu, Sunazuka, Toshiaki, Ōmura, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857236/
https://www.ncbi.nlm.nih.gov/pubmed/35181691
http://dx.doi.org/10.1038/s41598-022-06729-z
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author Horikoshi, Ryo
Goto, Kimihiko
Mitomi, Masaaki
Oyama, Kazuhiko
Hirose, Tomoyasu
Sunazuka, Toshiaki
Ōmura, Satoshi
author_facet Horikoshi, Ryo
Goto, Kimihiko
Mitomi, Masaaki
Oyama, Kazuhiko
Hirose, Tomoyasu
Sunazuka, Toshiaki
Ōmura, Satoshi
author_sort Horikoshi, Ryo
collection PubMed
description Afidopyropen, a novel insecticide, is a derivative of pyripyropene A, which is produced by the filamentous fungus Penicillium coprobium. Afidopyropen has strong insecticidal activity against aphids and is currently used as a control agent of sucking pests worldwide. In this study, we summarized the biological properties and field efficacies of its derivatives against agricultural pests using official field trials conducted in Japan. Afidopyropen showed good residual efficacies against a variety of aphids, whiteflies and other sucking pests under field conditions. Furthermore, toxicological studies revealed its safety profiles against nontarget organisms, such as the honeybee, natural enemies and other beneficial insects, as well as mammals. Thus, afidopyropen is a next-generation agrochemical for crop protection that has a low environmental impact.
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spelling pubmed-88572362022-02-22 Afidopyropen, a novel insecticide originating from microbial secondary extracts Horikoshi, Ryo Goto, Kimihiko Mitomi, Masaaki Oyama, Kazuhiko Hirose, Tomoyasu Sunazuka, Toshiaki Ōmura, Satoshi Sci Rep Article Afidopyropen, a novel insecticide, is a derivative of pyripyropene A, which is produced by the filamentous fungus Penicillium coprobium. Afidopyropen has strong insecticidal activity against aphids and is currently used as a control agent of sucking pests worldwide. In this study, we summarized the biological properties and field efficacies of its derivatives against agricultural pests using official field trials conducted in Japan. Afidopyropen showed good residual efficacies against a variety of aphids, whiteflies and other sucking pests under field conditions. Furthermore, toxicological studies revealed its safety profiles against nontarget organisms, such as the honeybee, natural enemies and other beneficial insects, as well as mammals. Thus, afidopyropen is a next-generation agrochemical for crop protection that has a low environmental impact. Nature Publishing Group UK 2022-02-18 /pmc/articles/PMC8857236/ /pubmed/35181691 http://dx.doi.org/10.1038/s41598-022-06729-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Horikoshi, Ryo
Goto, Kimihiko
Mitomi, Masaaki
Oyama, Kazuhiko
Hirose, Tomoyasu
Sunazuka, Toshiaki
Ōmura, Satoshi
Afidopyropen, a novel insecticide originating from microbial secondary extracts
title Afidopyropen, a novel insecticide originating from microbial secondary extracts
title_full Afidopyropen, a novel insecticide originating from microbial secondary extracts
title_fullStr Afidopyropen, a novel insecticide originating from microbial secondary extracts
title_full_unstemmed Afidopyropen, a novel insecticide originating from microbial secondary extracts
title_short Afidopyropen, a novel insecticide originating from microbial secondary extracts
title_sort afidopyropen, a novel insecticide originating from microbial secondary extracts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857236/
https://www.ncbi.nlm.nih.gov/pubmed/35181691
http://dx.doi.org/10.1038/s41598-022-06729-z
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