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The METTL5-TRMT112 N(6)-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation

Ribosomal RNAs (rRNAs) have long been known to carry chemical modifications, including 2′O-methylation, pseudouridylation, N(6)-methyladenosine (m(6)A), and N(6,6-)dimethyladenosine. While the functions of many of these modifications are unclear, some are highly conserved and occur in regions of the...

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Detalles Bibliográficos
Autores principales: Sepich-Poore, Caraline, Zheng, Zhong, Schmitt, Emily, Wen, Kailong, Zhang, Zijie Scott, Cui, Xiao-Long, Dai, Qing, Zhu, Allen C., Zhang, Linda, Sanchez Castillo, Arantxa, Tan, Haiyan, Peng, Junmin, Zhuang, Xiaoxi, He, Chuan, Nachtergaele, Sigrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857481/
https://www.ncbi.nlm.nih.gov/pubmed/35033535
http://dx.doi.org/10.1016/j.jbc.2022.101590

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