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Separable structural requirements for cDNA synthesis, nontemplated extension, and template jumping by a non-LTR retroelement reverse transcriptase

Broad evolutionary expansion of polymerase families has enabled specialization of their activities for distinct cellular roles. In addition to template-complementary synthesis, many polymerases extend their duplex products by nontemplated nucleotide addition (NTA). This activity is exploited for lab...

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Detalles Bibliográficos
Autores principales:	Pimentel, Sydney C., Upton, Heather E., Collins, Kathleen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857657/ https://www.ncbi.nlm.nih.gov/pubmed/35065960 http://dx.doi.org/10.1016/j.jbc.2022.101624

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