Colistin-induced Bartter-like Syndrome: Ponder before Treatment!

Bartter-like syndrome (BLS) is a constellation of biochemical abnormalities which include metabolic alkalosis, hypokalemia, hypocalcemia, hypomagnesemia with normal kidney function. BLS is a very rare syndrome and can be induced by certain diseases, antibiotics, diuretics, and antineoplastic drugs....

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Autores principales: Kumari, Anju, Gupta, Poonam, Verma, Himanshu, Kumar, Ajay, Thakur, Preeti, Sharma, Kavish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857716/
https://www.ncbi.nlm.nih.gov/pubmed/35712740
http://dx.doi.org/10.5005/jp-journals-10071-24117
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author Kumari, Anju
Gupta, Poonam
Verma, Himanshu
Kumar, Ajay
Thakur, Preeti
Sharma, Kavish
author_facet Kumari, Anju
Gupta, Poonam
Verma, Himanshu
Kumar, Ajay
Thakur, Preeti
Sharma, Kavish
author_sort Kumari, Anju
collection PubMed
description Bartter-like syndrome (BLS) is a constellation of biochemical abnormalities which include metabolic alkalosis, hypokalemia, hypocalcemia, hypomagnesemia with normal kidney function. BLS is a very rare syndrome and can be induced by certain diseases, antibiotics, diuretics, and antineoplastic drugs. Colistin is a polymicrobial bactericidal drug and currently re-emerged as the only salvation therapy against multidrug resistant bacilli especially in critically ill patients at intensive care units. Only an anecdotal case report of colistin-induced Bartter-like syndrome has been reported. We here report a case series of four critically ill patients who were on treatment with colistin and presented with serious metabolic disturbances. HOW TO CITE THIS ARTICLE: Kumari A, Gupta P, Verma H, Kumar A, Thakur P, Sharma K. Colistin-induced Bartter-like Syndrome: Ponder before Treatment! Indian J Crit Care Med 2022;26(2):239–243.
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spelling pubmed-88577162022-06-15 Colistin-induced Bartter-like Syndrome: Ponder before Treatment! Kumari, Anju Gupta, Poonam Verma, Himanshu Kumar, Ajay Thakur, Preeti Sharma, Kavish Indian J Crit Care Med Case Report Bartter-like syndrome (BLS) is a constellation of biochemical abnormalities which include metabolic alkalosis, hypokalemia, hypocalcemia, hypomagnesemia with normal kidney function. BLS is a very rare syndrome and can be induced by certain diseases, antibiotics, diuretics, and antineoplastic drugs. Colistin is a polymicrobial bactericidal drug and currently re-emerged as the only salvation therapy against multidrug resistant bacilli especially in critically ill patients at intensive care units. Only an anecdotal case report of colistin-induced Bartter-like syndrome has been reported. We here report a case series of four critically ill patients who were on treatment with colistin and presented with serious metabolic disturbances. HOW TO CITE THIS ARTICLE: Kumari A, Gupta P, Verma H, Kumar A, Thakur P, Sharma K. Colistin-induced Bartter-like Syndrome: Ponder before Treatment! Indian J Crit Care Med 2022;26(2):239–243. Jaypee Brothers Medical Publishers 2022-02 /pmc/articles/PMC8857716/ /pubmed/35712740 http://dx.doi.org/10.5005/jp-journals-10071-24117 Text en Copyright © 2022; The Author(s). https://creativecommons.org/licenses/by-nc/4.0/© The Author(s). 2022 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Kumari, Anju
Gupta, Poonam
Verma, Himanshu
Kumar, Ajay
Thakur, Preeti
Sharma, Kavish
Colistin-induced Bartter-like Syndrome: Ponder before Treatment!
title Colistin-induced Bartter-like Syndrome: Ponder before Treatment!
title_full Colistin-induced Bartter-like Syndrome: Ponder before Treatment!
title_fullStr Colistin-induced Bartter-like Syndrome: Ponder before Treatment!
title_full_unstemmed Colistin-induced Bartter-like Syndrome: Ponder before Treatment!
title_short Colistin-induced Bartter-like Syndrome: Ponder before Treatment!
title_sort colistin-induced bartter-like syndrome: ponder before treatment!
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857716/
https://www.ncbi.nlm.nih.gov/pubmed/35712740
http://dx.doi.org/10.5005/jp-journals-10071-24117
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