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PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is characterized by robust microgliosis and phenotypic changes that accompany disease pathogenesis. Accumulating evidence from genetic studies suggests the importance of phospholipase C γ 2 (PLCG2) in late-onset AD (LOAD) pathophysiology. However, the role of PLC...

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Detalles Bibliográficos
Autores principales:	Tsai, Andy P., Dong, Chuanpeng, Lin, Peter Bor-Chian, Messenger, Evan J., Casali, Brad T., Moutinho, Miguel, Liu, Yunlong, Oblak, Adrian L., Lamb, Bruce T., Landreth, Gary E., Bissel, Stephanie J., Nho, Kwangsik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857783/ https://www.ncbi.nlm.nih.gov/pubmed/35180881 http://dx.doi.org/10.1186/s13073-022-01022-0

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