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FOXQ1-mediated SIRT1 upregulation enhances stemness and radio-resistance of colorectal cancer cells and restores intestinal microbiota function by promoting β-catenin nuclear translocation

BACKGROUND: Resistance of colorectal cancer (CRC) cells to radiotherapy considerably contributes to poor clinical outcomes of CRC patients. Microarray profiling in this study revealed the differentially expressed forkhead box Q1 (FOXQ1) in CRC, and thus we aimed to illustrate the role of FOXQ1 in CR...

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Detalles Bibliográficos
Autores principales:	Yang, Mei, Liu, Qian, Dai, Maolin, Peng, Renqun, Li, Xinghui, Zuo, Wei, Gou, Juhua, Zhou, Feixue, Yu, Shuangjiang, Liu, Hao, Huang, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857837/ https://www.ncbi.nlm.nih.gov/pubmed/35183223 http://dx.doi.org/10.1186/s13046-021-02239-4

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