Overexpression of OASL upregulates TET1 to induce aberrant activation of CD4(+) T cells in systemic sclerosis via IRF1 signaling

BACKGROUND: Systemic sclerosis (SSc), an autoimmune disease with unknown etiology and pathogenesis, is characterized by abnormal autoimmunity, vascular dysfunction, and progressive fibrosis of skin and organs. Studies have shown that a key factor in the pathogenesis of SSc is aberrant activation of...

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Detalles Bibliográficos
Autores principales: Zeng, Zhuotong, Wang, Yaoyao, Xiao, Yangfan, Zheng, Jie, Liu, Ruizhen, He, Xinglan, Yu, Jiangfan, Tang, Bingsi, Qiu, Xiangning, Tang, Rui, Shi, Yaqian, Xiao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857842/
https://www.ncbi.nlm.nih.gov/pubmed/35183246
http://dx.doi.org/10.1186/s13075-022-02741-w

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