MeCP2 confers 5-fluorouracil resistance in gastric cancer via upregulating the NOX4/PKM2 pathway

BACKGROUND: Increasing evidence suggests that aberrant methylation is involved in 5-fluorouracil (5-FU) resistance in gastric cancer (GC). Our previous work has identified that Methyl-CpG binding protein 2 (MeCP2) promotes GC progression by binding to the methylation sites of promoter regions of spe...

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Detalles Bibliográficos
Autores principales: Qin, Yannan, Ma, Xiaoping, Guo, Chen, Cai, Shuang, Ma, Hailin, Zhao, Lingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857846/
https://www.ncbi.nlm.nih.gov/pubmed/35180871
http://dx.doi.org/10.1186/s12935-022-02489-y

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