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Impact of distant peptide substrate residues on enzymatic activity of SlyD
Peptidyl-prolyl isomerases (PPIases) catalyze intrinsically slow and often rate-limiting isomerization of prolyl-peptide bonds in unfolded or partially folded proteins, thereby speeding up the folding process and preventing misfolding. They often possess binding and chaperone domains in addition to...
Autores principales: | Pazicky, Samuel, Werle, Anna-Leoni A., Lei, Jian, Löw, Christian, Weininger, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858294/ https://www.ncbi.nlm.nih.gov/pubmed/35184231 http://dx.doi.org/10.1007/s00018-022-04179-4 |
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