Targeting autophagy peptidase ATG4B with a novel natural product inhibitor Azalomycin F4a for advanced gastric cancer

Advanced gastric cancer (GCa) remains highly lethal due to the lack of effective therapies. Identifying promising therapeutic targets and developing effective treatment against GCa are urgently needed. Through mRNA and protein analysis of GCa clinical tumor samples, we found that autophagy-related g...

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Detalles Bibliográficos
Autores principales: Zhong, Lin, Yang, Bin, Zhang, Zhenhua, Wang, Junfeng, Wang, Xiaojuan, Guo, Yinfeng, Huang, Weifeng, Wang, Qianqian, Cai, Guodi, Xia, Fan, Zhou, Shengning, Ma, Shuai, Nie, Yichu, Lei, Jinping, Li, Min, Liu, Peiqing, Deng, Wenbin, Liu, Yonghong, Han, Fanghai, Wang, Junjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858318/
https://www.ncbi.nlm.nih.gov/pubmed/35184132
http://dx.doi.org/10.1038/s41419-022-04608-z

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