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Lansoprazole-induced osteoporosis via the IP3R- and SOCE-mediated calcium signaling pathways

BACKGROUND: Many clinical studies have shown a correlation between proton pump inhibitors (PPIs) and osteoporosis or fractures. The purpose of this study was to establish a murine model of chronic oral PPI administration to verify whether PPIs caused bone metabolic impairment and investigate the rel...

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Detalles Bibliográficos
Autores principales: Cheng, Ziping, Liu, Yangjie, Ma, Mengyuan, Sun, Shiyu, Ma, Zengqing, Wang, Yu, Yu, Liyuan, Qian, Xuping, Sun, Luning, Zhang, Xuehui, Liu, Yun, Wang, Yongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858482/
https://www.ncbi.nlm.nih.gov/pubmed/35183103
http://dx.doi.org/10.1186/s10020-022-00448-x