HOXA7 promotes the metastasis of KRAS mutant colorectal cancer by regulating myeloid-derived suppressor cells

BACKGROUND: KRAS mutation accounts for 30–50% of human colorectal cancer (CRC) cases. Due to the scarcity of effective treatment options, KRAS mutant CRC is difficult to treat in the clinic. Metastasis is still the major cause of the high mortality associated with KRAS mutant CRC, but the exact mech...

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Detalles Bibliográficos
Autores principales: Dang, Yunzhi, Yu, Jiao, Zhao, Shuhong, Cao, Ximing, Wang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858502/
https://www.ncbi.nlm.nih.gov/pubmed/35183163
http://dx.doi.org/10.1186/s12935-022-02519-9

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