Rare coding variants in RCN3 are associated with blood pressure

BACKGROUND: While large genome-wide association studies have identified nearly one thousand loci associated with variation in blood pressure, rare variant identification is still a challenge. In family-based cohorts, genome-wide linkage scans have been successful in identifying rare genetic variants...

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Detalles Bibliográficos
Autores principales: He, Karen Y., Kelly, Tanika N., Wang, Heming, Liang, Jingjing, Zhu, Luke, Cade, Brian E., Assimes, Themistocles L., Becker, Lewis C., Beitelshees, Amber L., Bielak, Lawrence F., Bress, Adam P., Brody, Jennifer A., Chang, Yen-Pei Christy, Chang, Yi-Cheng, de Vries, Paul S., Duggirala, Ravindranath, Fox, Ervin R., Franceschini, Nora, Furniss, Anna L., Gao, Yan, Guo, Xiuqing, Haessler, Jeffrey, Hung, Yi-Jen, Hwang, Shih-Jen, Irvin, Marguerite Ryan, Kalyani, Rita R., Liu, Ching-Ti, Liu, Chunyu, Martin, Lisa Warsinger, Montasser, May E., Muntner, Paul M., Mwasongwe, Stanford, Naseri, Take, Palmas, Walter, Reupena, Muagututi’a Sefuiva, Rice, Kenneth M., Sheu, Wayne H.-H., Shimbo, Daichi, Smith, Jennifer A., Snively, Beverly M., Yanek, Lisa R., Zhao, Wei, Blangero, John, Boerwinkle, Eric, Chen, Yii-Der Ida, Correa, Adolfo, Cupples, L. Adrienne, Curran, Joanne E., Fornage, Myriam, He, Jiang, Hou, Lifang, Kaplan, Robert C., Kardia, Sharon L. R., Kenny, Eimear E., Kooperberg, Charles, Lloyd-Jones, Donald, Loos, Ruth J. F., Mathias, Rasika A., McGarvey, Stephen T., Mitchell, Braxton D., North, Kari E., Peyser, Patricia A., Psaty, Bruce M., Raffield, Laura M., Rao, D. C., Redline, Susan, Reiner, Alex P., Rich, Stephen S., Rotter, Jerome I., Taylor, Kent D., Tracy, Russell, Vasan, Ramachandran S., Morrison, Alanna C., Levy, Daniel, Chakravarti, Aravinda, Arnett, Donna K., Zhu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858539/
https://www.ncbi.nlm.nih.gov/pubmed/35183128
http://dx.doi.org/10.1186/s12864-022-08356-4

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