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Efficient link prediction in the protein–protein interaction network using topological information in a generative adversarial network machine learning model

BACKGROUND: The investigation of possible interactions between two proteins in intracellular signaling is an expensive and laborious procedure in the wet-lab, therefore, several in silico approaches have been implemented to narrow down the candidates for future experimental validations. Reformulatin...

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Detalles Bibliográficos
Autores principales: Balogh, Olivér M., Benczik, Bettina, Horváth, András, Pétervári, Mátyás, Csermely, Péter, Ferdinandy, Péter, Ágg, Bence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858570/
https://www.ncbi.nlm.nih.gov/pubmed/35183129
http://dx.doi.org/10.1186/s12859-022-04598-x