Persistent high glucose induced EPB41L4A‐AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non‐histones

BACKGROUND: Persistent hyperglycemia decreases the sensitivity of insulin‐sensitive organs to insulin, owing to which cells fail to take up and utilize glucose, which exacerbates the progression of type 2 diabetes mellitus (T2DM). lncRNAs' abnormal expression is reported to be associated with t...

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Detalles Bibliográficos
Autores principales: Liao, Weijie, Xu, Naihan, Zhang, Haowei, Liao, Weifang, Wang, Yanzhi, Wang, Songmao, Zhang, Shikuan, Jiang, Yuyang, Xie, Weidong, Zhang, Yaou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858623/
https://www.ncbi.nlm.nih.gov/pubmed/35184403
http://dx.doi.org/10.1002/ctm2.699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858623/
https://www.ncbi.nlm.nih.gov/pubmed/35184403
http://dx.doi.org/10.1002/ctm2.699

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