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Persistent high glucose induced EPB41L4A‐AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non‐histones
BACKGROUND: Persistent hyperglycemia decreases the sensitivity of insulin‐sensitive organs to insulin, owing to which cells fail to take up and utilize glucose, which exacerbates the progression of type 2 diabetes mellitus (T2DM). lncRNAs' abnormal expression is reported to be associated with t...
Autores principales: | Liao, Weijie, Xu, Naihan, Zhang, Haowei, Liao, Weifang, Wang, Yanzhi, Wang, Songmao, Zhang, Shikuan, Jiang, Yuyang, Xie, Weidong, Zhang, Yaou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858623/ https://www.ncbi.nlm.nih.gov/pubmed/35184403 http://dx.doi.org/10.1002/ctm2.699 |
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