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The CTCF/LncRNA‐PACERR complex recruits E1A binding protein p300 to induce pro‐tumour macrophages in pancreatic ductal adenocarcinoma via directly regulating PTGS2 expression

BACKGROUND: Tumour‐associated macrophages (TAMs) play an important role in promoting the progression of pancreatic ductal adenocarcinoma (PDAC). Here, we aimed to study the epigenetic mechanisms in regulating pro‐tumour M2‐polarised TAMs in the PDAC tumour microenvironment. METHODS: This study was c...

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Detalles Bibliográficos
Autores principales:	Liu, Yihao, Wang, Xuelong, Zhu, Youwei, Cao, Yizhi, Wang, Liwen, Li, Fanlu, Zhang, Yu, Li, Ying, Zhang, Zhiqiang, Luo, Jiaxin, Deng, Xiaxing, Peng, Chenghong, Wei, Gang, Chen, Hao, Shen, Baiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858628/ https://www.ncbi.nlm.nih.gov/pubmed/35184402 http://dx.doi.org/10.1002/ctm2.654

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