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Clinical characteristics of children hospitalized for COVID-19()
INTRODUCTION: Most SARS-CoV2 infections in the pediatric population are asymptomatic or with mild symptoms, with a minimal proportion of severe cases described as SARS-CoV2-associated multi-system inflammatory syndrome (MIS-C). The objective was to describe the clinical and epidemiological character...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier España, S.L.U.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858688/ https://www.ncbi.nlm.nih.gov/pubmed/35224201 http://dx.doi.org/10.1016/j.medcle.2021.11.004 |
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author | Luz Romero, Rosa María Illán Ramos, Marta Berzosa Sánchez, Arantxa Joyanes Abancens, Belén Baos Muñoz, Elvira Ramos Amador, José Tomás |
author_facet | Luz Romero, Rosa María Illán Ramos, Marta Berzosa Sánchez, Arantxa Joyanes Abancens, Belén Baos Muñoz, Elvira Ramos Amador, José Tomás |
author_sort | Luz Romero, Rosa María |
collection | PubMed |
description | INTRODUCTION: Most SARS-CoV2 infections in the pediatric population are asymptomatic or with mild symptoms, with a minimal proportion of severe cases described as SARS-CoV2-associated multi-system inflammatory syndrome (MIS-C). The objective was to describe the clinical and epidemiological characteristics of pediatric patients admitted with confirmed diagnosis of SARS-CoV2 infection from the beginning of the pandemic until May 2021. METHODS: Retrospective observational study of pediatric patients hospitalized with confirmed COVID-19, in a tertiary hospital. Epidemiological and clinical data, additional tests, treatments administered and evolution were collected. RESULTS: 30 patients were included, classified into 3 groups according to diagnosis: respiratory infection, MIS-C and compatible symptoms. The patients with pneumonia were associated with age older, comorbidities and lymphopenia. MIS-C were more serious patients, with marked laboratory involvement and greater admission to PICU. Most of these were secondary cases of contact in the family environment. DISCUSSION: The most frequent clinical manifestations of COVID-19 in children are mild-moderate respiratory with good evolution. MIS-C is another form of expression of SARS-COV2 infection of greater severity, but usually with good prognosis after early diagnosis and frequent PICU admission. |
format | Online Article Text |
id | pubmed-8858688 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier España, S.L.U. |
record_format | MEDLINE/PubMed |
spelling | pubmed-88586882022-02-22 Clinical characteristics of children hospitalized for COVID-19() Luz Romero, Rosa María Illán Ramos, Marta Berzosa Sánchez, Arantxa Joyanes Abancens, Belén Baos Muñoz, Elvira Ramos Amador, José Tomás Med Clin (Engl Ed) Clinical Report INTRODUCTION: Most SARS-CoV2 infections in the pediatric population are asymptomatic or with mild symptoms, with a minimal proportion of severe cases described as SARS-CoV2-associated multi-system inflammatory syndrome (MIS-C). The objective was to describe the clinical and epidemiological characteristics of pediatric patients admitted with confirmed diagnosis of SARS-CoV2 infection from the beginning of the pandemic until May 2021. METHODS: Retrospective observational study of pediatric patients hospitalized with confirmed COVID-19, in a tertiary hospital. Epidemiological and clinical data, additional tests, treatments administered and evolution were collected. RESULTS: 30 patients were included, classified into 3 groups according to diagnosis: respiratory infection, MIS-C and compatible symptoms. The patients with pneumonia were associated with age older, comorbidities and lymphopenia. MIS-C were more serious patients, with marked laboratory involvement and greater admission to PICU. Most of these were secondary cases of contact in the family environment. DISCUSSION: The most frequent clinical manifestations of COVID-19 in children are mild-moderate respiratory with good evolution. MIS-C is another form of expression of SARS-COV2 infection of greater severity, but usually with good prognosis after early diagnosis and frequent PICU admission. Elsevier España, S.L.U. 2022-04-08 2022-02-21 /pmc/articles/PMC8858688/ /pubmed/35224201 http://dx.doi.org/10.1016/j.medcle.2021.11.004 Text en © 2021 Elsevier España, S.L.U. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Clinical Report Luz Romero, Rosa María Illán Ramos, Marta Berzosa Sánchez, Arantxa Joyanes Abancens, Belén Baos Muñoz, Elvira Ramos Amador, José Tomás Clinical characteristics of children hospitalized for COVID-19() |
title | Clinical characteristics of children hospitalized for COVID-19() |
title_full | Clinical characteristics of children hospitalized for COVID-19() |
title_fullStr | Clinical characteristics of children hospitalized for COVID-19() |
title_full_unstemmed | Clinical characteristics of children hospitalized for COVID-19() |
title_short | Clinical characteristics of children hospitalized for COVID-19() |
title_sort | clinical characteristics of children hospitalized for covid-19() |
topic | Clinical Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858688/ https://www.ncbi.nlm.nih.gov/pubmed/35224201 http://dx.doi.org/10.1016/j.medcle.2021.11.004 |
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