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Clinical characteristics of children hospitalized for COVID-19()

INTRODUCTION: Most SARS-CoV2 infections in the pediatric population are asymptomatic or with mild symptoms, with a minimal proportion of severe cases described as SARS-CoV2-associated multi-system inflammatory syndrome (MIS-C). The objective was to describe the clinical and epidemiological character...

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Autores principales: Luz Romero, Rosa María, Illán Ramos, Marta, Berzosa Sánchez, Arantxa, Joyanes Abancens, Belén, Baos Muñoz, Elvira, Ramos Amador, José Tomás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier España, S.L.U. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858688/
https://www.ncbi.nlm.nih.gov/pubmed/35224201
http://dx.doi.org/10.1016/j.medcle.2021.11.004
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author Luz Romero, Rosa María
Illán Ramos, Marta
Berzosa Sánchez, Arantxa
Joyanes Abancens, Belén
Baos Muñoz, Elvira
Ramos Amador, José Tomás
author_facet Luz Romero, Rosa María
Illán Ramos, Marta
Berzosa Sánchez, Arantxa
Joyanes Abancens, Belén
Baos Muñoz, Elvira
Ramos Amador, José Tomás
author_sort Luz Romero, Rosa María
collection PubMed
description INTRODUCTION: Most SARS-CoV2 infections in the pediatric population are asymptomatic or with mild symptoms, with a minimal proportion of severe cases described as SARS-CoV2-associated multi-system inflammatory syndrome (MIS-C). The objective was to describe the clinical and epidemiological characteristics of pediatric patients admitted with confirmed diagnosis of SARS-CoV2 infection from the beginning of the pandemic until May 2021. METHODS: Retrospective observational study of pediatric patients hospitalized with confirmed COVID-19, in a tertiary hospital. Epidemiological and clinical data, additional tests, treatments administered and evolution were collected. RESULTS: 30 patients were included, classified into 3 groups according to diagnosis: respiratory infection, MIS-C and compatible symptoms. The patients with pneumonia were associated with age older, comorbidities and lymphopenia. MIS-C were more serious patients, with marked laboratory involvement and greater admission to PICU. Most of these were secondary cases of contact in the family environment. DISCUSSION: The most frequent clinical manifestations of COVID-19 in children are mild-moderate respiratory with good evolution. MIS-C is another form of expression of SARS-COV2 infection of greater severity, but usually with good prognosis after early diagnosis and frequent PICU admission.
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spelling pubmed-88586882022-02-22 Clinical characteristics of children hospitalized for COVID-19() Luz Romero, Rosa María Illán Ramos, Marta Berzosa Sánchez, Arantxa Joyanes Abancens, Belén Baos Muñoz, Elvira Ramos Amador, José Tomás Med Clin (Engl Ed) Clinical Report INTRODUCTION: Most SARS-CoV2 infections in the pediatric population are asymptomatic or with mild symptoms, with a minimal proportion of severe cases described as SARS-CoV2-associated multi-system inflammatory syndrome (MIS-C). The objective was to describe the clinical and epidemiological characteristics of pediatric patients admitted with confirmed diagnosis of SARS-CoV2 infection from the beginning of the pandemic until May 2021. METHODS: Retrospective observational study of pediatric patients hospitalized with confirmed COVID-19, in a tertiary hospital. Epidemiological and clinical data, additional tests, treatments administered and evolution were collected. RESULTS: 30 patients were included, classified into 3 groups according to diagnosis: respiratory infection, MIS-C and compatible symptoms. The patients with pneumonia were associated with age older, comorbidities and lymphopenia. MIS-C were more serious patients, with marked laboratory involvement and greater admission to PICU. Most of these were secondary cases of contact in the family environment. DISCUSSION: The most frequent clinical manifestations of COVID-19 in children are mild-moderate respiratory with good evolution. MIS-C is another form of expression of SARS-COV2 infection of greater severity, but usually with good prognosis after early diagnosis and frequent PICU admission. Elsevier España, S.L.U. 2022-04-08 2022-02-21 /pmc/articles/PMC8858688/ /pubmed/35224201 http://dx.doi.org/10.1016/j.medcle.2021.11.004 Text en © 2021 Elsevier España, S.L.U. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Clinical Report
Luz Romero, Rosa María
Illán Ramos, Marta
Berzosa Sánchez, Arantxa
Joyanes Abancens, Belén
Baos Muñoz, Elvira
Ramos Amador, José Tomás
Clinical characteristics of children hospitalized for COVID-19()
title Clinical characteristics of children hospitalized for COVID-19()
title_full Clinical characteristics of children hospitalized for COVID-19()
title_fullStr Clinical characteristics of children hospitalized for COVID-19()
title_full_unstemmed Clinical characteristics of children hospitalized for COVID-19()
title_short Clinical characteristics of children hospitalized for COVID-19()
title_sort clinical characteristics of children hospitalized for covid-19()
topic Clinical Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858688/
https://www.ncbi.nlm.nih.gov/pubmed/35224201
http://dx.doi.org/10.1016/j.medcle.2021.11.004
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