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Storming the castle: A case report of multi‐system dysregulation in a child with Castleman disease

Castleman disease is a non‐clonal, lymphoproliferative disorder rarely seen in children. Presented is a 12‐year‐old male with progressive abdominal pain, vomiting, and fever. Diagnostic testing revealed multi‐organ system involvement and the diagnosis was ultimately made with tissue biopsy. Marked d...

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Detalles Bibliográficos
Autores principales: DeMarsh, Samantha J., Kendel, Nicole E., Bacha, Christine, Ardoin, Stacy P., Kahwash, Samir, Rose, Melissa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858787/
https://www.ncbi.nlm.nih.gov/pubmed/35369387
http://dx.doi.org/10.1002/ccr3.5491
Descripción
Sumario:Castleman disease is a non‐clonal, lymphoproliferative disorder rarely seen in children. Presented is a 12‐year‐old male with progressive abdominal pain, vomiting, and fever. Diagnostic testing revealed multi‐organ system involvement and the diagnosis was ultimately made with tissue biopsy. Marked disease regression occurred after high‐dose steroids and continued interleukin‐6 inhibition.