Alteration of Gut Microbiome and Correlated Amino Acid Metabolism Contribute to Hyperuricemia and Th17-Driven Inflammation in Uox-KO Mice

Although gut dysbiosis had been demonstrated to be an important factor affecting hyperuricemia (HUA) and gout, little is known for its potential mechanistic connections. In this study, Uox-KO mice model that with spontaneously developed pronounced HUA and urate nephropathy was used to explore the pa...

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Detalles Bibliográficos
Autores principales: Song, Siyue, Lou, Yu, Mao, Yingying, Wen, Xianghui, Fan, Moqi, He, Zhixing, Shen, Yang, Wen, Chengping, Shao, Tiejuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858814/
https://www.ncbi.nlm.nih.gov/pubmed/35197978
http://dx.doi.org/10.3389/fimmu.2022.804306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858814/
https://www.ncbi.nlm.nih.gov/pubmed/35197978
http://dx.doi.org/10.3389/fimmu.2022.804306

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