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Alteration of Gut Microbiome and Correlated Amino Acid Metabolism Contribute to Hyperuricemia and Th17-Driven Inflammation in Uox-KO Mice
Although gut dysbiosis had been demonstrated to be an important factor affecting hyperuricemia (HUA) and gout, little is known for its potential mechanistic connections. In this study, Uox-KO mice model that with spontaneously developed pronounced HUA and urate nephropathy was used to explore the pa...
Autores principales: | Song, Siyue, Lou, Yu, Mao, Yingying, Wen, Xianghui, Fan, Moqi, He, Zhixing, Shen, Yang, Wen, Chengping, Shao, Tiejuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858814/ https://www.ncbi.nlm.nih.gov/pubmed/35197978 http://dx.doi.org/10.3389/fimmu.2022.804306 |
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