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Indole Hydrazide Compound IHZ-1 Induces Apoptosis and Autophagy via Activation of ROS/JNK Pathway in Hepatocellular Carcinoma

Hepatocellular carcinoma is one of the most common primary malignant tumors of the digestive system. Compound 5-chloro-N′-(2,4-dimethoxybenzylidene)-1H-indole-2-carbohydrazide (IHZ-1/ZJQ-24) is a novel indole hydrazide derivative. In a recent study, we demonstrated that IHZ-1 inhibits tumor growth a...

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Detalles Bibliográficos
Autores principales:	Sun, Manting, Liu, Dan, Yuan, Yang, Dan, Juhua, Jia, Shuting, Luo, Ying, Liu, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858831/ https://www.ncbi.nlm.nih.gov/pubmed/35198445 http://dx.doi.org/10.3389/fonc.2022.811747

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