Metastatic neuroendocrine tumors mimicking as primary ocular disease

PURPOSE: To report two cases of metastatic neuroendocrine tumors masquerading as primary ocular disease. OBSERVATIONS: Case 1 is a 38-year-old man who was referred with subacute onset diplopia and fluctuating ptosis suggestive of myasthenia gravis. Case 2 is a 21-year-old man who presented with blur...

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Detalles Bibliográficos
Autores principales: Shen, Alice, Haghighi, Arezu, Liang, Tom, Lee, On-Tat, Gange, William, DeBoer, Charles, Akhter, Mashal, Saber, Maria Sibug, Patel, Vivek R, Berry, Jesse L, Gokoffski, Kimberly Kinga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858882/
https://www.ncbi.nlm.nih.gov/pubmed/35243162
http://dx.doi.org/10.1016/j.ajoc.2022.101425
Descripción
Sumario:PURPOSE: To report two cases of metastatic neuroendocrine tumors masquerading as primary ocular disease. OBSERVATIONS: Case 1 is a 38-year-old man who was referred with subacute onset diplopia and fluctuating ptosis suggestive of myasthenia gravis. Case 2 is a 21-year-old man who presented with blurry vision and was found to have a pigmented ciliary body mass and retinal detachment suggestive of uveal melanoma. Both patients were ultimately diagnosed with metastatic neuroendocrine tumors. CONCLUSIONS AND IMPORTANCE: Neuroendocrine tumors, though rare and infrequently metastatic to the eye and orbit, can initially present with ocular signs. A broad differential and careful consideration of ocular and systemic symptoms are critical in such challenging cases.

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