Cargando…

Circulating α-Klotho Levels in Relation to Cardiovascular Diseases: A Mendelian Randomization Study

BACKGROUND: Several studies have reported a protective role of circulating α-Klotho on cardiovascular diseases (CVD); however, the causality remains unclear. We aim to elucidate whether genetically predicted circulating α-Klotho levels were causally associated with the risk of coronary artery diseas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Xingang, Chen, Lu, He, Yuxian, Zheng, Liangrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859151/ https://www.ncbi.nlm.nih.gov/pubmed/35197934 http://dx.doi.org/10.3389/fendo.2022.842846

Ejemplares similares

Self-Reported Walking Pace and Risk of Cardiovascular Diseases: A Two-Sample Mendelian Randomization Study
por: Chen, Lu, et al.
Publicado: (2022)

Obstructive sleep apnea and atrial fibrillation: insights from a bidirectional Mendelian randomization study
por: Chen, Lu, et al.
Publicado: (2022)

No causal effect of tea consumption on cardiovascular diseases: A two-sample Mendelian randomization study
por: Chen, Lu, et al.
Publicado: (2022)

Association of Autism Spectrum Disorder, Neuroticism, and Subjective Well-Being With Cardiovascular Diseases: A Two-Sample Mendelian Randomization Study
por: Sun, Xingang, et al.
Publicado: (2021)

GWAS meta-analysis followed by Mendelian randomization revealed potential control mechanisms for circulating α-Klotho levels
por: Gergei, Ingrid, et al.
Publicado: (2021)

Serum uric acid levels and risk of cardiovascular disease in type 2 diabetes: results from a cross-sectional study and Mendelian randomization analysis
por: He, Ying, et al.
Publicado: (2023)

Genetic liability to asthma and risk of cardiovascular diseases: A Mendelian randomization study
por: Chen, Heng, et al.
Publicado: (2022)

Association between sarcopenia-related traits and cardiovascular diseases: a bi-directional Mendelian randomization study
por: Liu, Xu, et al.
Publicado: (2023)

Visceral adipose tissue and risk of COVID-19 susceptibility, hospitalization, and severity: A Mendelian randomization study
por: Chen, Lu, et al.
Publicado: (2022)

Cardiac Troponin I and Risk of Stroke: A Mendelian Randomization Study
por: Chen, Heng, et al.
Publicado: (2022)

Higher levels of serum α-Klotho are longitudinally associated with less central obesity in girls experiencing weight gain
por: Carreras-Badosa, Gemma, et al.
Publicado: (2023)

Causality between urate levels with sarcopenia-related traits: a bi-directional Mendelian randomization study
por: Lin, Yanze, et al.
Publicado: (2023)

α-Klotho Expression in Human Tissues
por: Lim, Kenneth, et al.
Publicado: (2015)

Association between serum Klotho levels and the prevalence of diabetes among adults in the United States
por: Wang, Kai, et al.
Publicado: (2022)

Causal relationship between circulating lipid traits and periodontitis: univariable and multivariable Mendelian randomization
por: Hu, Gaofu, et al.
Publicado: (2023)

Aging and antioxidants: the impact of dietary carotenoid intakes on soluble klotho levels in aged adults
por: He, Xingkang, et al.
Publicado: (2023)

Circulating insulin-like growth factor-1 and risk of lung diseases: A Mendelian randomization analysis
por: Jiang, Sujing, et al.
Publicado: (2023)

The impact of SGLT2 inhibitors on αKlotho in renal MDCK and HK-2 cells
por: Wolf, Lisa, et al.
Publicado: (2023)

Association between soluble α-klotho and mortality risk in middle-aged and older adults
por: Chuang, Min-Hsiang, et al.
Publicado: (2023)

Klotho is upregulated in human cardiomyopathy independently of circulating Klotho levels
por: Poelzl, G., et al.
Publicado: (2018)

Klotho, Aging, and the Failing Kidney
por: Buchanan, Sarah, et al.
Publicado: (2020)

Association of Cortisol Levels With Neuropsychiatric Functions: A Mendelian Randomization Analysis
por: Zhou, Xiang, et al.
Publicado: (2019)

Mendelian randomization study of thyroid function and anti-Müllerian hormone levels
por: Liang, Zhu, et al.
Publicado: (2023)

Bidirectional Mendelian randomization study of insulin-related traits and risk of ovarian cancer
por: Wang, Xinghao, et al.
Publicado: (2023)

Relationship Between Serum Amino Acid Levels and Bone Mineral Density: A Mendelian Randomization Study
por: Cui, Zhiyong, et al.
Publicado: (2021)

Inflammatory arthritis and eye diseases: a Mendelian randomization study
por: Nie, Xinlin, et al.
Publicado: (2023)

Serum α-Klotho associated with oral health among a nationally representative sample of US adults
por: Chen, Guo-Qiang, et al.
Publicado: (2022)

Circulating levels of cytokines and risk of cardiovascular disease: a Mendelian randomization study
por: Wei, Tao, et al.
Publicado: (2023)

Causal relationship between circulating immune cells and the risk of type 2 diabetes: a Mendelian randomization study
por: Li, Jin, et al.
Publicado: (2023)

Assessing Causal Associations of Atopic Dermatitis With Heart Failure and Other Cardiovascular Outcomes: A Mendelian Randomization Study
por: Chen, Heng, et al.
Publicado: (2022)

Plasma lipid levels and risk of retinal vascular occlusion: A genetic study using Mendelian randomization
por: Zheng, Changwei, et al.
Publicado: (2022)

Sex Steroids and Osteoarthritis: A Mendelian Randomization Study
por: Yan, Yi-Shang, et al.
Publicado: (2021)

Use of Mendelian Randomization to Examine Causal Inference in Osteoporosis
por: Zheng, Jie, et al.
Publicado: (2019)

New Insights into the Mechanism of Action of Soluble Klotho
por: Dalton, George D., et al.
Publicado: (2017)

Acute Impacts of Different Types of Exercise on Circulating α-Klotho Protein Levels
por: Iturriaga, Tamara, et al.
Publicado: (2021)

Osteoporosis and sarcopenia-related traits: A bi-directional Mendelian randomization study
por: Liu, Chao, et al.
Publicado: (2022)

COVID‐19 and sarcopenia-related traits: a bidirectional Mendelian randomization study
por: Liu, Chao, et al.
Publicado: (2023)

Relationship of Soluble Klotho and Early Stage of Diabetic Nephropathy: A Systematic Review and Meta-Analysis
por: Xin, Caihong, et al.
Publicado: (2022)

Causal Association of Type 2 Diabetes Mellitus and Glycemic Traits With Cardiovascular Diseases and Lipid Traits: A Mendelian Randomization Study
por: Huang, Mingkai, et al.
Publicado: (2022)

An examination of causal associations and shared risk factors for diabetes and cardiovascular diseases in the East Asian population: A Mendelian randomization study
por: Guo, Yulin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9pe1n7mb8qq31m6s0r6udi07v9