Tofacitinib Suppresses Natural Killer Cells In Vitro and In Vivo: Implications for Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative disease with few therapeutic options. However, the immune system, including natural killer (NK) cells, is linked to ALS progression and may constitute a viable therapeutic ALS target. Tofacitinib is an FDA-approved immuno...

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Detalles Bibliográficos
Autores principales: Figueroa-Romero, Claudia, Monteagudo, Alina, Murdock, Benjamin J., Famie, Joshua P., Webber-Davis, Ian F., Piecuch, Caroline E., Teener, Samuel J., Pacut, Crystal, Goutman, Stephen A., Feldman, Eva L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859451/
https://www.ncbi.nlm.nih.gov/pubmed/35197969
http://dx.doi.org/10.3389/fimmu.2022.773288

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