Multi-omics-based label-free metabolic flux inference reveals obesity-associated dysregulatory mechanisms in liver glucose metabolism

Glucose homeostasis is maintained by modulation of metabolic flux. Enzymes and metabolites regulate the involved metabolic pathways. Dysregulation of glucose homeostasis is a pathological event in obesity. Analyzing metabolic pathways and the mechanisms contributing to obesity-associated dysregulati...

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Detalles Bibliográficos
Autores principales: Uematsu, Saori, Ohno, Satoshi, Tanaka, Kaori Y., Hatano, Atsushi, Kokaji, Toshiya, Ito, Yuki, Kubota, Hiroyuki, Hironaka, Ken-ichi, Suzuki, Yutaka, Matsumoto, Masaki, Nakayama, Keiichi I., Hirayama, Akiyoshi, Soga, Tomoyoshi, Kuroda, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859528/
https://www.ncbi.nlm.nih.gov/pubmed/35243212
http://dx.doi.org/10.1016/j.isci.2022.103787

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