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Celecoxib Synergistically Enhances MLN4924-Induced Cytotoxicity and EMT Inhibition Via AKT and ERK Pathways in Human Urothelial Carcinoma

MLN4924 is a specific small-molecule inhibitor of NEDD8-activating enzyme (NAE) that blocks the neddylation modification cascade. Several I/II/III clinical trials suggested that MLN4924 exerts an antitumor effect against various malignancies. However, recent studies have also found that MLN4924 acti...

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Detalles Bibliográficos
Autores principales:	Xiong, Shida, Huang, Wei, Liu, Xiaoqiang, Chen, Qian, Ding, Yi, Huang, Haoxuan, Zhang, Ru, Guo, Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859662/ https://www.ncbi.nlm.nih.gov/pubmed/35176901 http://dx.doi.org/10.1177/09636897221077921

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